A rude, vulgar invective expressing disdain, contempt, disgust, or anger to someone (about something). Primarily heard in US. I've taken enough of the boss's crap—he can stick this job up his ass! Bill: "You're acting like a fool, Dave. You need to sober up and get your life in order." Dave: "Ah, stick it up your ass, Bill! You don't know what's best for me!"